Key Note Speakers
Head of the Department of Analytical Biochemistry
University of Groningen
Rainer Bischoff started his career in protein-related research when joining the biotechnology company Transgene, applying mass spectrometry to the characterization of recombinant proteins. He continued his career at AstraZeneca R&D as head of the Target Development section before joining the Faculty of Mathematics and Natural Sciences at the University of Groningen as full professor of Analytical Biochemistry in 2001. Research interests of the Analytical Biochemistry Department focus on biomarker discovery and validation, bioinformatics, the analysis of biopharmaceutical proteins and the development of novel instrumental analytical techniques. Rainer Bischoff is director of the interfaculty mass spectrometry center and head of the Biomarker Development Center (http://biomarkerdevelopmentcenter.nl/). Rainer Bischoff authored more than 200 peer-reviewed publications, a number of book chapters and is inventor on 14 patents.
Herbert H. Lindner
Herbert Lindner established a bioanalytical research group focusing on the development of high-resolution methods for the separation and identification of post-translationally modified proteins, to investigate their biological significance. Separation methods based on capillary electrophoresis (CE), RPC, HILIC and mass spectrometry were developed in his lab. He is Head of the Protein Micro-Analysis Facility at Innsbruck Medical University, which offers a wide range of analytical methods and services to support the work of other research scientist in the University. At present, one of his main research interests focuses on the evaluation of CE coupled to mass spectrometry as an alternative proteomics tool to nanoLC-ESI-MS..
Associate Professor KTH Royal Institute of Technology School of Biotechnology
Divison of Protein Technology, Sweden
My Hedhammar is Associate Professor at the School of Biotechnology, Royal Institute of Technology (KTH) in Stockholm. Her background is in protein engineering, and this has lately been utilized for the development of intelligent materials for biomedical applications. The focus of her current research group is to use recombinant techniques to functionalize spider silk proteins in a way that preserve their self-assembly property and allows production of bioactive silk for e.g. tissue engineering applications.
Bioseparation Engineering Group
Technical University of Munich, Germany
Sonja Berensmeier leads the Bioseparation Engineering Group at the Technical University of Munich since 2009, after several years as a group leader at the Karlsruhe Institute of Technology in the area of biofunctional surfaces. She meets the challenge for applied integration of molecular biology, biotechnology, particle technology, and process engineering. The focus of the current research is process intensification by adsorptive and extractive separation methods. In the field of adsorbents she is specialized in magnetic and conductive particles.
Biopharmaceuticals and Biomaterials Development Group
CICS-UBI – Health Sciences Research Center
University of Beira Interior, Covilhã, Portugal
Cristina Dias-Cabral is Assistant Professor at the Department of Chemistry, University of Beira Interior in Covilhã, Portugal and an integrated member of the CICS-UBI – Health Sciences Research Center at the same University. She is currently working in the field of downstream processing and characterization of large biomolecules. Fundamental aspects of adsorption of different types of biomolecules on different types of chromatographic supports with application in optimization and scale-up of chromatographic units is one of her special focus. Since 2010, date when she established a Flow Microcalorimetry laboratory at CICS-UBI, she has been characterizing thermodynamically the adsorption mechanisms of several biomolecules on different chromatographic supports used in downstream processing in order to understand their mechanism of interaction with the support. Work done in collaboration with different national and international research groups.
Director Downstream Processing
Synthon Biopharmaceuticals B.V.
Michel Eppink is Director Downstream Processing at the Biopharmaceutical Development Division of Synthon Biopharmaceuticals BV developing purification/formulation processes for biopharmaceutical proteins and involved in different (inter) national collaborations for new technologies in the field of purification and formulation development. Next to that Michel is Special Professor at the Department of Bioprocess Engineering at Wageningen University and Research Centre heading a group of PhD candidates in the research of new purification/ analytical techniques for proteins/lipids/carbohydrates from different eukaryotic organisms (e.g. mammalian cell lines, macroalgae, microalgae, yeast) embedded in (inter) national collaborations.
Department „Bioengineering & Biosystems“, Institute of Functional Interfaces
Karlsruhe Institute of Technology (KIT)
Matthias Franzreb is professor at the Karlsruhe Institute of Technology and leads the department of Bioengineering and Biosystems of the Institute of Functional Interfaces. Since more than 20 years, his group develops magnet technology and its applications in the fields of chemical- and bioengineering. The designed, characterized, and commercialized systems handle volumes ranging from a few µL in bioanalytical systems up to several m³/h in large-scale magnetic separators. Besides magnet technology his current research is focused to chromatography driven by physical stimuli (temperature, electrical potential) as well as the emerging field of 3D-printing in biotechnology.
School of Biotechnology, AlbaNova University Center
KTH – Royal Institute of Technology, Stockholm, Sweden
Sophia Hober is Professor of Molecular Biotechnology at KTH, Stockholm, Sweden. The focus of her current research group is development of predictable and robust systems for protein purification and detection by protein design and various selection methodologies. Her key scientific achievements include design and development of gene fusion systems for selective ion-exchange purification and improvements of the alkaline tolerance of protein A and protein G for industrial purification of IgG/HSA (Currently a product sold by GE-Health care). Moreover, small bispecific protein domains with ability to strongly and selectively bind to two different proteins recently have been developed.
Department of Biotechnology
University of Natural Resources and Life Sciences Vienna
Austrian Centre of Industrial Biotechnology
Alois Jungbauer serves since 1986 as a professor at the Department of Biotechnology at the University of Natural Resources and Life Sciences, Vienna. He teaches Protein Technology and Downstream Processing and Bioprocess Engineering. He also acts as area head and Dep. Director of Research in the Austrian Centre of Industrial Biotechnology. He is currently working in the field of bioengineering of proteins, plasmids and viruses with special focus on expression, downstream processing and characterization of large biomolecules.
As a proliferate researcher he has more than 300 publications on recombinant protein production and bioseparation, 15 patents and 12 book contributions and recently a monograph entitled “Protein Chromatography , Process Development and Scale Up”. He is executive editor and co-founder of Biotechnology Journal, and member of editorial boards from numerous journals in the area of biochemical engineering.
Faculty of Chemistry and Chemical Technology
University of Ljubljana, Slovenia
Aleš Podgornik, Ph.D., is by profession chemical engineer and has worked for 20 years in the field of biochemical engineering, especially in the downstream processing of macromolecules. He worked as CSO and R&D head for companies BIA and BIA Separations for more than a decade, currently he is a professor of chemical engineering on Faculty of Chemistry and Chemical Technology, University of Ljubljana, as well as Head of bioprocessing technologies in COBIK. His research interest is biochromatography and bioprocessing including continuous processes.